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The Clinical Septomics research group is led by University Professor Frank Martin Brunkhorst.

CS group leader small

A physician in internal medicine and intensive care, Professor Brunkhorst has been Specialist Registrar at the Clinic for Anaesthesiology and Intensive Care of Jena University Hospital since 2001. In addition, he has held the Paul Martini Foundation Professorship for Clinical Sepsis Research since 2008. His research priorities are the diagnosis and treatment of serious infections and sepsis. He has many years’ experience of initiating and coordinating clinical trials, for example as part of the Competence Network Sepsis (SepNet), which is funded by the Federal Ministry of Education and Research (BMBF). He is a founding member and General Secretary of the German Sepsis Society (Deutsche Sepsis Gesellschaft e.V.), as well as a founding member and deputy chair of the German Sepsis Aid (Deutsche Sepsis-Hilfe e.V.). For his dedication and his contributions to clinical sepsis research, he was awarded the Federal Cross of Merit in 2005 and in 2009 he received the Paul Martini prize for excellence in clinical sepsis research.

Awards / Grants

  • 2009 | Paul Martini prize for excellence in clinical sepsis research
  • 2005 | Cross of the Order of Merit of the Federal Republic of Germany for his dedication and his contributions to the research on severe infections and sepsis


  • Bloos F, Marshall JC, Dellinger RP, Vincent JL, Gutierrez G, Rivers E, Balk RA, Laterre PF, Angus DC, Reinhart K, Brunkhorst FM (2011) Multinational, observational study of procalcitonin in ICU patients with pneumonia requiring mechanical ventilation: a multicenter observational study.
    Crit Care 15(2): R88
  • Reinhart K, Brunkhorst FM, Bone HG, Bardutzky J, Dempfle CE, Forst H, Gastmeier P, Gerlach H, Gründling M, John S, Kern W, Kreymann G, Krüger W, Kujath P, Marggraf G, Martin J, Mayer K, Meier-Hellmann A, Oppert M, Putensen C, Quintel M, Ragaller M, Rossaint R, Seifert H, Spies C, Stüber F, Weiler N, Weimann A, Werdan K, Welte T, German Interdisciplinary Association for Intensive and Emergency Care Medicine; German Sepsis Society (2010) Prevention, diagnosis, treatment, and follow-up care of sepsis. First revision of the S2k Guidelines of the German Sepsis Society (DSG) and the German Interdisciplinary Association for Intensive and Emergency Care Medicine (DIVI).
    Anaesthesist 59(4): 347-70
  • Reinhart K, Hartog CS, Brunkhorst FM (2010) Hydroxyethyl starches: plus ca change, plus C'est la Même chose.
    Anesthesiology 112(3): 756-7
  • Brunkhorst FM, Engel C, Bloos, F, Meier-Hellmann A, Ragaller, M, Weiler N, Moerer O. Gruendling M, Oppert M, Grond S, Olthoff D, Jaschinski U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhnt E, Kiehntopf M, Hartog C, Natanson C, Loeffler M, Reinhart K for the German Competence Network Sepsis (SepNet) (2008) A Trial of Intensive Insulin Therapy and Pentastarch Resuscitation in Severe Sepsis.
    N. Engl. J. Med. 358: 125-39
  • Engel C, Brunkhorst FM, Bone HG, Brunkhorst R, Gerlach H, Grond S, Gruendling M, Huhle G, Jaschinski U, John S, Mayer K, Oppert M, Olthoff D, Quintel M, Ragaller M, Rossaint R, Stuber F, Weiler N, Welte T, Bogatsch H, Hartog C, Loeffler M, Reinhart K. (2007) Epidemiology of sepsis in Germany: results from a national prospective multicenter study.
    Intensive Care Med. 33(4): 606-18
Paul Martini

Clinical Septomics wird unterstützt von

Universitätsklinikum Jena

Septomics is a research center of the:

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Septomics is funded by:

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